HONG KONG, December 22, 2025 /PRNewswire/ — Japanese skin care brand Yii collaborates with ANDS Corporation (“ANDS”), a subsidiary of Rohto Pharmaceutical Co., Ltd., to explore the niche skin care market with pharmaceutical-grade scientific excellence. The collaboration combines over 60 years of ANDS formulation expertise with Yii’s oriental philosophy of “Nourishing Beauty Effortlessly”, delivering proven effectiveness and high security for sensitive, barrier-compromised and prematurely aging skin.
Where Eastern philosophy meets Japanese craftsmanship
Modern lifestyles, environmental pressures and internal factors contribute to increasingly unstable skin conditions, leading to growing demand among Asian consumers for “high-efficacy, low-irritation” skincare. Rooted in the Yi Jing principle of perpetual change, Yii advocates skincare that adapts to seasonal changes, environmental changes and one’s immediate physical and mental state, going beyond rigid and static classifications such as “oily” or “dry.”
Since its founding in 1960, ANDS has continued the century-old pharmaceutical legacy of the Rohto family, adhering to its mission “to help customers love themselves more”. Its trusted series, including SATYS’α and Grace Program, have won the trust of a wide audience. This partnership represents a deep resonance in the shared belief that “skin health must return to science and balance.” ANDS brings pharmaceutical-grade rigor with a focus on “visible results,” while Yii embodies a “Harmonize with Grace, Nourish Beauty Effortlessly” philosophy as a way of life. Together, they aim to translate Japan’s best medical dedication to skincare into solutions that truly address the dynamic needs of Asian skin, allowing users to radiate confidence from within, reflecting the aligned vision, values and purpose of Yii and ANDS.
Three pillars of pharmaceutical quality assurance
To translate this vision into reliable products, Yii and ANDS have established a quality benchmark that exceeds conventional standards:
- Official Japanese “quasi-drug” certification: All eight Yii products are certified as “quasi-drugs” under Japan’s Pharmaceuticals and Medical Devices Act. This classification falls between cosmetics and pharmaceuticals, requiring strict approval and monitoring by the Ministry of Health, Labor and Welfare to ensure both safety and effectiveness, without the risk of cumulative toxicity from long-term use.
- Manufactured in Japanese pharmaceutical grade GMP facilities: ANDS’ in-house factory is one of the few in the Japanese cosmetics industry to hold Good Manufacturing Practice (GMP) certification, ensuring that quality and safety meet the strictest standards of the highest level. The factory is also ISO 16128 certified, guaranteeing the use of natural ingredients throughout the production process and their purity from source to formulation.
- Exclusive 3D skin model technology: Using a proprietary 3D skin model that replaces traditional animal testing, the technology accurately simulates the multi-layered structure and response of real skin. It not only evaluates ingredient penetration but also scientifically predicts long-term product safety. ANDS is one of five Japanese companies equipped with this advanced technology.
Yii formulations are gentle and highly safe, suitable even for the delicate eye area. They are free of Sudan Red, artificial fragrances, dyes, mineral oil, parabens and other irritants.
Yii is now officially available in the Japanese market and has been launched in select LOG-ON stores in Hong Kong. The brand will continue to develop products tailored to the subtle needs of Asian skin, bringing Japanese skincare know-how and pharmaceutical quality to more consumers. Visitors are invited to benefit from a personalized skin consultation by professional skin specialists at the counters, integrating the “Nourishing Effortless Beauty” philosophy into their daily ritual.
About Yii
Founded in 2025, Yii products are manufactured in pharmaceutical-grade GMP facilities in Japan, hold “quasi-drug” certification from the Japanese Ministry of Health, Labor and Welfare, and pass allergy testing consistent with US FDA standards. The formulas are gentle and safe for the eye area, specially designed for sensitive, barrier-compromised and prematurely aging skin. Using highly penetrating, high concentration natural ingredients combined with a dynamic nourishing approach, Yii helps skin adapt to seasonal changes and return to a healthy, balanced state.
Website: https://yii-skin.com/
About ANDS
Established in 1960 by Yasuhiro Yamada, former executive general director of Rohto Pharmaceutical Co., Ltd. and former president of Mentholatum Japan. ANDS Corporation specializes in the research, development and production of premium skin care products. Adhering to Japanese pharmaceutical standards for production and safety testing, its products are celebrated for their exceptional safety and visible effectiveness.
Media Contact: Abby Yung | abby@yii-skin.com | +852 6259 6793
Selected LOG-ON stores: Times Square, Harbor City, Festival Walk, Metroplaza, Tuen Mun Town Plaza
Social Media: Facebook: Yii Hong Kong | Instagram: yii_official_hongkong
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