The brand sets a new benchmark for Chinese skincare
SHANGHAI, April 26, 2026 /PRNewswire/ — Late nights, bedtime procrastination, and back-to-back weekend social plans: These modern habits are taking a visible toll on the skin. New data shows that the average age at which the first signs of aging appear in China has changed by about four years between 2018 and 2023. Researchers point to a clear link between premature wrinkles and today’s highly stressful, sleep-deprived lifestyles.[1].
On April 23, the second China Anti-Fatigue-Aging Tech Forum and the launch of CHANDO’s seventh generation rejuvenating repair essence (Xiao Zi Ping) concluded at TANK Shanghai. The event brought together experts from various fields to discuss skin aging and rejuvenation in the context of Chinese consumers’ skin care needs. In the spotlight: the improved version of seventh generation CHANDOthe signature anti-aging essence linked to fatigue. Powered by HiMurchaSin® Yeast, the formula helps consumers achieve better skincare results without changing their daily routines. The launch also featured a surprise appearance from AI-native virtual singer YURI, as well as other celebrities. A modern art of light and shadow mixed with natural elements of Himalayan inspiration, offering a resolutely avant-garde aesthetic.
Scientists examine factors responsible for accelerated skin aging
Hectic lives accelerate skin aging among Chinese consumers. According to a study reported by China National Radio (CNR), a research team led by Wang Sijia from the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, analyzed facial skin aging and lifestyle factors using large-scale, multi-point data from the Chinese population. The study found that the inflection point of overall aging of wrinkles in China’s population arrived about four years earlier in 2023 than in 2018, indicating an increasing trend. earlier onset, faster progression and shortened aging cycle[1]. The research also noted a decrease in sleep duration and a younger age of starting smoking and drinking, indicating an increase in fatigue-focused lifestyles. Multiple lifestyle factors related to fatigue were closely related to the early onset of facial wrinkles.
In fact, skin aging due to a fatigue-induced lifestyle is a biological process that can be addressed scientifically. Deng Haiteng, a full professor at the School of Life Sciences at Tsinghua University, explained the science behind modulating the skin’s aging process. According to Deng, life stress can impair mitochondria – the energy factories inside human cells. The key to skin rejuvenation, he says, is turning on the cellular energy switch: PGC1α, a critical target of mitochondrial regeneration.
From the laboratory to the vanity: how an ingredient made in China became the heart of a new anti-aging formula
To address this biological mechanism, the R&D team led by Dr. Zou Yue, Vice President and Chief Scientist of CHANDO Group, used AI-based computational biology to screen and engineer more than 2.8 million yeast proteins. The result was HiMurchaSin® Ultra Anti-Peptide, a recently developed exclusive ingredient. According to CHANDO, HiMurchaSin® Ultra Anti-Peptide penetrates the skin 8.5 times better than traditional tetrapeptides[2]. It targets PGC1α – the mitochondrial energy switch, increasing its expression by 1.7x[3]. This supports cellular energy production, promotes cell and collagen renewal, helps improve skin firmness and reduce the appearance of wrinkles.
Zheng Chunying, Chairman and Chairman of CHANDO Group, said: “Basic ingredients are the core of beauty in cosmetics. » He emphasized that CHANDO has always prioritized in-house R&D and manufacturing. The aim is to control costs, efficiency and supply stability so that Chinese consumers can access products that meet or exceed leading global standards at more affordable prices. “We want to make advanced skin care technology accessible to everyone,” Zheng said.
WINTERThe new rejuvenating restorative essence offers visible results: up to 5 years younger skin in 8 weeks[4] Leveraging technological innovation and ingredient-driven beauty, CHANDO officially unveiled the seventh generation of its rejuvenating repair essence. The new serum offers comprehensive improvements in effectiveness, user experience and packaging.
Strengths of the formula:
- Contains the world’s first HiMurchaSin® Ultra Anti-Peptidic
- Contains 2x HiMurchaSin concentrate® (7 million yeast essences per drop)
- Precisely targets PGC1α, the mitochondrial energy switch, to help restore a more youthful appearance to skin
- Blended with 99.9% L-Ergothioneine and polar probiotic extracts
Key benefits: Firming, anti-wrinkle, brightening and repairing, all in one bottle. According to CHANDO, the formula targets aging due to fatigue linked to modern lifestyles. Clinical claim: skin up to five years younger in just eight weeks.
User experience: The serum has a lightweight, water-like texture that absorbs quickly without leaving a sticky residue. A subtle, soothing scent helps reduce feelings of stress and fatigue. The redesigned dropper and reservoir ensure every drop is used without waste. Every detail, from effectiveness to experience, responds directly to real consumer feedback.
To validate performance, CHANDO partnered with SGS, a third-party testing organization, to conduct the Anti-Aging Record 21-day real-world user test. Participants reported visibly brighter skin, fewer fine lines, and a more youthful, radiant complexion after consistent use. For those who often stay up late or work long hours, the seventh generation Rejuvenating Repair Essence is a targeted solution to fatigue-related skin concerns.
AI Performer and Celebrity Appearances Bring Energy to Launch Event
The launch of CHANDO Rejuvenation Repairing Essence was designed as a high-tech and immersive experience, reshaping consumers’ perception of the beauty brand. YURI, the AI-native virtual singer, debuted with a science-themed stand-up routine. The virtual interpreter presented a sharp and witty analysis of skincare ingredients, providing a scientific perspective on the new serum. CHANDO’s youth brand ambassador then made a surprise appearance, interacting with the audience and sharing his personal experience with the product, embodying the idea of staying energetic and looking great despite a busy and stressful lifestyle. From scientific innovation to interactive storytelling, CHANDO has revealed a new, younger side of Chinese beauty brands: bold, connected and fun. The message to consumers: A skincare brand can be both results-driven and engaging.
With this technology launch, CHANDO demonstrated the strength and imagination of a Chinese skincare brand. By leveraging science and technology, the company aims to help consumers adopt a more effective skincare routine without changing their current lifestyle. The seventh generation CHANDO Rejuvenating Restorative Essence could well be an interesting solution to combat visible skin aging in today’s hectic urban life.
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[1] Source: According to a report from China National Radio (CNR), a research team led by Wang Sijia from the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, conducted a quantitative analysis of facial skin aging and lifestyle factors using large-scale, multi-point data from the Chinese population. |
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[2] 8.5x: refers to the penetration of HiMurchaSin® Ultra Anti-Peptide which is 8.5 times greater than that of tetrapeptide-10. Internal data from the CHANDO R&D center. |
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[3] 1.7x: HiMurchaSin® Ultra Anti-Peptide increased PGC1α mRNA expression to 1.76 times the level of the control group, approximately 170% of the initial value. Internal data from the CHANDO R&D center. |
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[4] “Five years less in just eight weeks”: based on third-party effectiveness testing. Results of instrumental tests carried out on 32 Chinese volunteers aged 22 to 50 after eight weeks of use of the product. Individual results may vary. |
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